Vascular Bleeding Disorders

Vascular bleeding disorders result from defects in blood vessels, typically causing petechiae, purpura, and bruising but, except for hereditary hemorrhagic telangiectasia, seldom leading to serious blood loss. Bleeding may result from deficiencies of vascular and perivascular collagen in Ehlers-Danlos syndrome and in other rare hereditary connective tissue disorders; eg, pseudoxanthoma elasticum, osteogenesis imperfecta, Marfan syndrome. Hemorrhage may be a prominent feature of scurvy or of Henoch-Schönlein purpura, a hypersensitivity vasculitis common during childhood. In vascular bleeding disorders, tests of hemostasis are usually normal. 

 

  • Marfan Syndrome
  • Autoerythrocyte Sensitization
  • Dysproteinemias Causing Vascular Purpura
  • Hereditary Hemorrhagic Telangiectasia
  • Purpura Simplex
  • Senile Purpura
  • Scurvy
  • Ehlers-Danlos Syndrome
  • Pseudoxanthoma Elasticum

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